The size, shape and number of dendritic spines in the brain may play a major role in whether someone gets Alzheimer’s disease, according to new research from the University of Alabama at Birmingham. Dendritic spines are sub-units of neurons that act as the connector to other neurons.
Seizure disorders — including epilepsy — are associated with pathological hyperexcitability in brain neurons. Unfortunately, there are limited available treatments that can prevent this hyperexcitability. However, University of Alabama at Birmingham researchers have found that inducing a biochemical alteration in brain proteins via the dietary supplement glucosamine was able to rapidly dampen that pathological hyperexcitability in rat and mouse models.