A new therapeutic avenue for Parkinson’s disease

Clearing senescent astrocytes prevents Parkinson’s in mouse model of sporadic disease. Systemic clearing of senescent astrocytes prevents Parkinson’s neuropathology and associated symptoms in a mouse model of sporadic disease, the type implicated in 95% of human cases.

Scientists find a role for Parkinson’s gene in the brain

NIH-funded mouse study suggests LRRK gene is needed for dopamine neuron health. A new study published in the journal Neuron sheds light on the normal function of LRRK2, the most common genetic cause for late-onset Parkinson’s disease. The study was supported by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health.