Newly ID’d role of major Alzheimer’s gene suggests possible therapeutic target
Blocking ApoE4 in brain may prevent nerve cell death, inflammation. A study led by researchers at Washington University School of Medicine in St. Louis shows that the presence of ApoE4 exacerbates the brain damage caused by toxic tangles of a different Alzheimer’s-associated protein: tau. In the absence of ApoE, tau tangles did very little harm to brain cells.
